Literature Review of Pharmacological Treatments for Neonatal Abstinence Syndrome

Literature Review of Pharmacological Treatments for Neonatal Abstinence Syndrome

Authors

  • Indri Faculty of Medicine, Tarumanagara University, Special Region of Jakarta, Indonesia
  • Ivanna Faculty of Medicine, Trisakti University, Special Region of Jakarta, Indonesia

Keywords:

Pharmacological Treatments, Neonatal Abstinence Syndrome

Abstract

Background: The literature on pharmacological treatments for Neonatal Abstinence Syndrome (NAS) underscores the complexity of managing this condition, which arises from in utero opioid exposure. The reviewed articles collectively emphasize the necessity of pharmacological interventions while advocating for a multifaceted approach that includes both pharmacological and non-pharmacological strategies to optimize outcomes for affected infants. Literature Review: Overall, the literature reflects a consensus on the necessity of pharmacological interventions for NAS while also emphasizing the importance of individualized treatment strategies that incorporate both pharmacological and non-pharmacological measures to optimize outcomes for affected infants. Conclusion: In conclusion, the literature indicates a consensus on the necessity of pharmacological interventions for NAS, while also emphasizing the importance of integrating non-pharmacological measures to enhance treatment outcomes. The ongoing dialogue about optimizing treatment protocols, exploring alternative pharmacotherapeutic agents, and addressing the long-term implications of these interventions remains critical as the prevalence of NAS continues to rise in the context of the opioid crisis.

References

Boyer, R., Gal, L., & Cline, M., 2018. The Effect of Breastfeeding and Rooming-In Care on Neonatal Abstinence Syndrome. [PDF]

K. Kraft, W., 2018. Buprenorphine in Neonatal Abstinence Syndrome.. [PDF]

Murphy-Oikonen, J. & McQueen, K., 2018. Outpatient pharmacologic weaning for neonatal abstinence syndrome: a systematic review. ncbi.nlm.nih.gov

K. M. Nargarathan, P., Modebelu, U., Marleime, K., & Ramesh, K., 2019. Pharmacologic Therapy for Neonatal Abstinence Syndrome. [PDF]

G Stefanides, A., 2019. Is Sublingual Buprenorphine Treatment Effective and Efficient When Compared to Traditional Neonatal Opium Solution (Morphine) in Treating Newborns with Neonatal Abstinence Syndrome?. [PDF]

Ceccanti, M., Blum, K., Bowirrat, A., A. Dennen, C., R. Braverman, E., Baron, D., Mclaughlin, T., Giordano, J., Gupta, A., W. Downs, B., Bagchi, D., Barh, D., Elman, I., K. Thanos, P., D. Badgaiyan, R., Edwards, D., & S. Gold, M., 2022. Future Newborns with Opioid-Induced Neonatal Abstinence Syndrome (NAS) Could Be Assessed with the Genetic Addiction Risk Severity (GARS) Test and Potentially Treated Using Precision Amino-Acid Enkephalinase Inhibition Therapy (KB220) as a Frontline Modality Instead of Potent Opioids. ncbi.nlm.nih.gov

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Published

2024-07-10

How to Cite

Literature Review of Pharmacological Treatments for Neonatal Abstinence Syndrome (I. Indri & I. Ivanna , Trans.). (2024). The Indonesian Journal of General Medicine, 2(5), 1-11. https://doi.org/10.70070/4bp8xv55