Positive Airway Pressure, Mortality, and Cardiovascular Risk in Older Adults With Sleep Apnea

Positive Airway Pressure, Mortality, and Cardiovascular Risk in Older Adults With Sleep Apnea

Authors

  • Albert Faculty of Medicine, Trisakti University, Special Region of Jakarta, Indonesia
  • Yohana Faculty of Medicine, Tarumanagara University, Special Region of Jakarta, Indonesia

Keywords:

Positive Airway Pressure, Mortality, Cardiovascular Risk, Older Adults, Sleep Apnea

Abstract

Background: The relationship between Positive Airway Pressure (PAP) therapy and its implications for mortality and cardiovascular risk among older adults with sleep apnea has garnered increasing attention in recent years. This literature review synthesizes findings from various studies to illuminate the multifaceted impacts of PAP therapy on health outcomes in this demographic. Literature Review: The literature on Positive Airway Pressure (PAP) therapy reveals a complex relationship between its use, mortality, and cardiovascular risk in older adults with sleep apnea. The studies reviewed provide substantial evidence that while PAP therapy is a cornerstone treatment for obstructive sleep apnea syndrome (OSAS), its efficacy in improving cardiovascular outcomes and reducing mortality is influenced by factors such as patient adherence and the severity of the condition. Conclusion: In conclusion, the literature collectively underscores the significance of PAP therapy in managing obstructive sleep apnea and its associated cardiovascular risks in older adults. While there is evidence supporting its benefits, particularly in reducing mortality and improving cardiovascular health, the overall effectiveness is heavily contingent upon patient adherence to treatment. Future research is essential to clarify the long-term benefits of PAP therapy and to develop strategies that enhance compliance, ultimately aiming to mitigate mortality and cardiovascular risks in this vulnerable population.

References

L. Nelson, M., 2014. Continuous Positive Airway Pressure Use and Mild Obstructive Sleep Apnea Syndrome (OSAS). [PDF]

Freedman, N., 2014. Improvements in current treatments and emerging therapies for adult obstructive sleep apnea. ncbi.nlm.nih.gov

E. Korcarz, C., Benca, R., H. Barnet, J., & H. Stein, J., 2016. Treatment of Obstructive Sleep Apnea in Young and Middle‐Aged Adults: Effects of Positive Airway Pressure and Compliance on Arterial Stiffness, Endothelial Function, and Cardiac Hemodynamics. ncbi.nlm.nih.gov

Pilar Resano-Barrio, M., Arroyo-Espliguero, R., Carmen Viana-Llamas, M., & Mediano, O., 2020. Obstructive Sleep Apnoea Syndrome: Continuous Positive Airway Pressure Therapy for Prevention of Cardiovascular Risk. ncbi.nlm.nih.gov

Mochol, J., Gawrys, J., Gajecki, D., Szahidewicz-Krupska, E., Martynowicz, H., & Doroszko, A., 2021. Cardiovascular Disorders Triggered by Obstructive Sleep Apnea—A Focus on Endothelium and Blood Components. ncbi.nlm.nih.gov

Yasir, M., Pervaiz, A., & Sankari, A., 2022. Cardiovascular Outcomes in Sleep-Disordered Breathing: Are We Under-estimating?. ncbi.nlm.nih.gov

Grzęda-Hałon, M., Poręba, M., Gut, G., Czerwińska, K., Gać, P., Martynowicz, H., Mazur, G., & Poręba, R., 2022. The effect of CPAP therapy on heart rate variability in patients with obstructive sleep apnea. ncbi.nlm.nih.gov

Peker, Y., Akdeniz, B., Altay, S., Balcan, B., Başaran, Özcan, Baysal, E., Çelik, A., Dursunoğlu, D., Dursunoğlu, N., Fırat, S., Gündüz Gürkan, C., Öztürk, Önder, Sezai Taşbakan, M., Aytekin, V., İtil, O., Çuhadaroğlu, Çağlar, Atalar, E., & Yıldırır, A., 2023. Obstructive Sleep Apnea and Cardiovascular Disease: Where Do We Stand?. ncbi.nlm.nih.gov

Stevens, D., Title, M., Spurr, K., & Morrison, D., 2024. Positive airway pressure therapy adherence and outcomes in obstructive sleep apnea: An exploratory longitudinal retrospective randomized chart review. ncbi.nlm.nih.gov

Downloads

Published

2024-07-12

How to Cite

Positive Airway Pressure, Mortality, and Cardiovascular Risk in Older Adults With Sleep Apnea (A. Albert & Y. Yohana , Trans.). (2024). The Indonesian Journal of General Medicine, 2(5), 12-26. https://doi.org/10.70070/hsb90050