Comprehensive Literature Review of Preoperative Tranexamic Acid for Treatment of Bleeding, Edema, and Ecchymosis in Patients Undergoing Rhinoplasty

Comprehensive Literature Review of Preoperative Tranexamic Acid for Treatment of Bleeding, Edema, and Ecchymosis in Patients Undergoing Rhinoplasty

Authors

  • Sylvia Faculty of Medicine, Maranatha Christian University, Bandung City, West Java, Indonesia
  • Viona Faculty of Medicine, Tarumanagara University, Special Region of Jakarta, Indonesia

Keywords:

Preoperative, Tranexamic Acid, Treatment of Bleeding, Edema, Ecchymosis, Patients Undergoing Rhinoplasty

Abstract

Background: The literature on the use of tranexamic acid (TXA) in rhinoplasty highlights its efficacy in managing intraoperative bleeding, postoperative edema, and ecchymosis. The foundational study by (Ping et al., 2019) conducted a systematic review and meta-analysis, establishing that TXA significantly reduces blood loss and enhances surgical field quality, which is critical for successful nasal surgeries. This study laid the groundwork for understanding the role of TXA in improving surgical outcomes, particularly in minimizing postoperative complications such as edema and ecchymosis around the eyelids. Literature Review: The article "Role of tranexamic acid in nasal surgery: A systemic review and meta-analysis of randomized control trial" by (Ping et al., 2019) provides a comprehensive evaluation of the efficacy of tranexamic acid (TXA) in reducing bleeding, edema, and ecchymosis in patients undergoing various forms of nasal surgery, including rhinoplasty. Conclusion: In conclusion, the collective evidence from these studies supports the use of TXA in rhinoplasty as an effective means to enhance surgical conditions and patient outcomes. However, there remains a critical need for further research to establish standardized dosing strategies and explore alternative administration routes to fully leverage TXA's potential benefits in this surgical field.

References

Ping, W., Zhao, Q., Sun, H., Lu, H., & Li, F., 2019. Role of tranexamic acid in nasal surgery: A systemic review and meta-analysis of randomized control trial. ncbi.nlm.nih.gov

D Locketz, G., N Lozada, K., & D Bloom, J., 2020. Tranexamic Acid in Aesthetic Facial Plastic Surgery: A Systematic Review of Evidence, Applications, and Outcomes. ncbi.nlm.nih.gov

Haddady-Abianeh, S., Rahmati, J., Delavari, C., & Molaei, H., 2022. Comparison of the Effect of Injectable Tranexamic Acid and Inhaled Desmopressin in Controlling Bleeding and Ecchymosis in Open Rhinoplasty. ncbi.nlm.nih.gov

Pontillo, V., Daval, M., Marc, M., & Ayache, D., 2024. Effects of Tranexamic Acid on Intraoperative Bleeding and Surgical Field Visualization During Middle Ear Surgery: A Narrative Review. ncbi.nlm.nih.gov

Kolasiński, J., Reysner, T., Kolenda, M., Kołacz, S., & Domagalska, M., 2024. A systematic review and meta-analysis of systematic and topical tranexamic acid administration in aesthetic plastic surgery. ncbi.nlm.nih.gov

Published

2024-07-09

How to Cite

Comprehensive Literature Review of Preoperative Tranexamic Acid for Treatment of Bleeding, Edema, and Ecchymosis in Patients Undergoing Rhinoplasty (S. Sylvia & V. Viona , Trans.). (2024). The Indonesian Journal of General Medicine, 2(5), 40-49. https://doi.org/10.70070/2k75t526